Pregnancy planning for some is limited to medical examination and taking the necessary vitamins, while others face a number of difficulties and difficulties. In some cases, this is due to a decrease in ovulatory function in a woman or the presence of diseases of the pelvic organs, often the ovaries.
What is ovulation
To understand how and how to stimulate ovulation, you must be able to determine its onset, to know the definition of this term. This is called the exit from the ovary of the egg into the cavity of the fallopian tube as a result of the rupture of the dominant follicle. It happens that a woman undergoes an anovulatory cycle, which can be repeated for several months in a row. This is due to the fact that the dominant follicle does not mature in the ovaries and the egg does not release for its subsequent fertilization into the uterine cavity. According to studies, about 25% of women face this problem.
Before contacting a doctor, a woman can determine a malfunction in the body at home. To do this, you need to observe how the menstrual cycle goes. For example, some note that the interval between bleeding has increased, and the discharge has become more scarce. These are indirect signs of the presence of hormonal failure and possible problems associated with the onset of ovulation.
Some women experienced in planning women measure basal temperature, noting its value in the graph. Conducting observations over several cycles allows us to talk about the reliability of the data. Do not exclude the changes in the body of a woman, which can be tracked by secretions. The fact of ovulation manifests itself in the form of transparent, viscous discharge similar to egg white.
However, the most obvious way is to conduct folliculometry, which allows you to visually determine the number of mature follicles, as well as the presence of a dominant among them. This study is carried out for several days before the start of the proposed ovulation. It also allows us to establish its absence.
Indications for stimulation
The main indications that are associated with the need to stimulate ovulation are the absence of pregnancy in a couple who, during the year, are trying to conceive, but all attempts are unsuccessful. If their age exceeds 35 years, then this period is reduced to six months. Only a qualified doctor can determine the need for additional assistance to the female body. Therefore, the indications for use and the need to take any drugs are judged after a series of studies and analyzes.
To achieve a positive result, folliculometry is prescribed, and patency of the fallopian tubes is also checked. If there are adhesions in the pipes, then the effect of stimulation will be zero. As for the growth and development of the dominant follicle, then ultrasound can determine how this process proceeds in the ovaries.
In the case of diagnosing problems associated with the onset of ovulation, the couple can offer several solutions, the last of which is the IVF program. This procedure involves not only the use of donor material, but also its own eggs, which will be subsequently fertilized. Accordingly, it is necessary to prepare the body for the dominant follicle to mature in the ovary. Before starting the manipulations, the doctor explains what stimulates ovulation with IVF, which vitamins and medications should be taken. They will help the body, if he himself can not cope.
Types of drugs for stimulation
Before stimulating ovulation, it is necessary to find out which drugs are prescribed in a particular case. When it comes to problems with the release of an egg to stimulate follicle rupture, hormones like Horagon, Ovitrel, Profaza, and Rotten are prescribed. Follicle-stimulating hormones (FSH) include Puregon and Gonal. They have a similar structure to the hormone naturally occurring in the female body. Drugs that help suppress estrogen increase FSH levels - Dufaston, Clomid, Klostilbegit, Serofen.
It is noteworthy that the process of stimulating the ovaries should not be resorted to too often, this leads to their depletion. The attending physician can tell you exactly how many times in a row you can stimulate ovulation, because he knows the medical history and controls the patient’s health. Constant medical monitoring of ovarian condition is also required.
While taking hormonal drugs, some women note the onset of side effects in the form of insomnia, pain in the lower back and lower abdomen, sweating, increased anxiety, weight gain. However, in most cases, reviews of stimulation agree that women do not experience severe discomfort while taking medications.
Hormonal stimulation drugs
When the question arises of how to stimulate ovulation, then doctors offer one of the leading means in medical practice - Klostilbegit. It refers to antiestrogenic drugs, which are available in tablet form. It is very specific in terms of action: it binds estrogen receptors of the pituitary gland and ovaries. If in the female body there is an insufficient amount of estrogen, then this drug contributes to a slight increase. Otherwise, when an excess of this hormone is noted, then “Klostilbegit” acts as an antiestrogenic agent.
Before starting the reception, many are interested in the reviews and results of Klostilbegit. In most cases, it has a positive effect, in the annotation to the drug it is also noted that its administration contributes to the onset of multiple pregnancy. For some couples planning this fact becomes very expected and positive. Therefore, it can be recommended to those who are thinking about how to stimulate ovulation to conceive twins.
It is worth remembering that there are contraindications that need to be studied before taking it. These include:
- Pituitary or pituitary tumors.
- Ovarian cysts (except for PCA syndrome (polycystic).
- Failures of the adrenal glands and thyroid gland.
- Lactose intolerance.
- Renal or liver failure.
- Endometriosis
This list is not final, but it contains the main diseases that prevent the use of “Klostilbegit”. The duration of admission is 5 days, before the onset of the expected ovulation. If the drug did not have the desired result, then its administration is stopped for 3 cycles and only then the course is repeated again.
Based on the opinion of doctors, it is worth noting that in most cases these are positive reviews. The results of Klostilbegit among patients are also estimated by high numbers. Many couples became happy parents thanks to this drug.
Vitamin therapy
Fans of traditional medicine know how and how to stimulate ovulation, what proportions of herbs must be added as raw materials for the preparation of decoction and infusion. One of the most popular herbs that stimulate the female body to produce progesterone is the pine forest. If the reason for the stimulation is not enough, then you should consult your doctor about the possibility of including decoction from this plant in the diet.
Do not do in this case without taking vitamins that stimulate ovulation. They enhance the functions of the body, in particular folic acid, potassium iodide, iron and vitamins D, E, A. Their intake is recommended to continue after pregnancy in order to properly establish the internal organs of the fetus, its nervous system and normal development. It is recommended to start taking vitamins from the first day of the cycle and not to stop them with the onset of pregnancy.
Some forums are full of various promotional offers, which supposedly can replace the effect of drugs. Do not delay the call to the doctor and remain in the hope that they will replace the proper treatment. The use of vitamins is recommended as concomitant therapy, but not a substitute.
Injections to improve ovulation
When it comes to what effective injections that stimulate ovulation exist, doctors answer: "" hCG "(chorionic gonadotropin) and" Gonal "." The first is also prescribed in combination with a drug such as Klostilbegit. Together they contribute to the development of hormones necessary for the onset of ovulation and to prevent the development of a follicular cyst. HCG injections contribute to the growth of a dominant follicle, which subsequently will allow ovulation to occur. If the female body has a deficiency in the production of progesterone, then this often becomes the cause of an unsuccessful pregnancy or the development of infertility.
HCG injections are prescribed in the process of preparing for IVF, when additional stimulation of ovulation is necessary. Typically, a dosage of 5000 units. is sufficient to achieve the desired result. Injections are carried out intramuscularly, while the most optimal place for introducing a needle is the stomach. This is explained by the fact that in this area the injection is less painful than if you do it in the gluteus muscle. The time for the introduction of hCG as an injection is determined jointly with the doctor after ultrasound monitoring.
"Gonal" is considered a less harmful hormonal drug, it is easier to tolerate and prevents the formation of cysts. This drug is used in the first week of the menstrual cycle, and the duration is determined based on the results of the analyzes, which reflects the level of estrogen. In the absence of a positive effect in the current month, the next dosage is doubled.
“Gonal” is produced in the form of a pen-syringe, which contains the required amount of the drug. Judging by user reviews, during the injection does not feel any painful symptoms. Clear instructions for use with Gonal F allow you to independently carry out the procedure at home. It is important to comply with all requirements for safe and proper storage of the pen-syringe, and control the dosage introduced. The use of funds in the form of a powder should be carried out under the supervision of the attending physician. This is due to the fact that the dose of follitropin depends on the solution for the preparation of the injection.
According to the instructions for use "Gonal F", a high probability of a multiple pregnancy. However, judging by the reviews, many couples who are already desperate to conceive one baby will be happy if they manage to get pregnant with twins or triplets at a time.
Dufaston
Many years of experience using this drug is no longer a discovery for anyone, nor are its positive properties. Therefore, questions such as whether Dufaston stimulates ovulation are being asked less and less. Most women who have experienced problems of conception and menstrual irregularities speak of Duphaston as a remedy that causes almost no side effects compared to its counterpart, Utrozhestan. It restores the cycle, contributes to the normalization of the luteal phase.
The active component dydrogesterone does not have a negative effect on the blood coagulation process, liver function, carbohydrate metabolism. The duration of taking Duphaston as a drug that promotes the onset of ovulation is from 3 to 6 months. The timing of admission is determined by the doctor, in particular, with insufficiency of the second phase - from 14 to 25 days of the menstrual cycle. It is advisable not to interrupt the drug without consulting a doctor.
The main indication for use is hormone replacement therapy. The drug allows you to save your pregnancy due to the fact that it stimulates the natural production of progesterone. Reviews of women who took the drug during planning, argue that it is well tolerated, there is no change in mood, sleep disturbances, which is more common in other hormonal drugs.
"Letrozole"
One of those drugs that can be used an unlimited number of times. Unlike Klostilbegit, which is used no more than 6 times during life, Letrozole is allowed to be used as much as needed. Naturally, it is necessary to coordinate his reception with the attending physician. Most women who use this drug live abroad. This is explained by the fact that abroad it has very great popularity and effectiveness. It is noted that pregnancy occurs already in the first cycle of the drug.
As stated in the instructions for Letrozole, it helps to reduce estradiol levels. This leads to the fact that the pituitary gland produces an increased amount of LH (luteinizing hormone) and FSH, which favorably affects the onset of ovulation. With the combined use of Letrozole with hCG injections, a better quality of the endometrium is noted. This has a positive effect on the likelihood of pregnancy and onset.
While taking this drug, women note the absence of unpleasant side effects that accompany them during the use of other hormonal drugs. In particular, weight, mood does not change, there are no hot flashes, sweating, dryness in the vagina. However, it is also noted that this tool is much more expensive than its counterparts.
The instructions for Letrozole say that it is used primarily as an antitumor drug. This is due to the fact that it is in the process of testing, and the effect on the ovulation process is still undergoing a study stage. Therefore, it is not recommended to use it as a means for self-medication.
Puregon
It contains follitropin beta, which is a follicle-stimulating hormone called Puregon. The instructions for use say that its use is indicated to stimulate superovulation. The drug is effective in terms of preparing for the IVF and ICSI procedure, as well as before performing intrauterine insemination, during the embryo transfer procedure.
Those who have problems with conception know firsthand how they stimulate ovulation with polycystic ovary. This drug is also indicated for the restoration of the anovulatory cycle, as well as in the absence of a positive therapeutic effect as a result of taking Clomiphene.
On sale, the drug is found in the form of a solution for the preparation of an injection. It is administered subcutaneously or intramuscularly, depending on the dosage. According to the instructions for use with Puregon, it can be 100, 150, 200 IU (the drug can be administered either intramuscularly or subcutaneously), 300, 600 or 900 IU - only subcutaneously.
In the process of therapy, constant monitoring of how the ovaries respond to this drug is necessary. According to reviews, positive results from the appointment of Puregon during IVF can occur as a result of its use over several cycles. If we are talking about a period of more than 4 months, then there is a decrease in its effectiveness. As soon as the results of an ultrasound study indicate a growth in the dominant follicle, “hCG” injections are added to this drug, which helps to retain the egg in the uterine cavity and the development of pregnancy. This measure is not necessary if there is an increased growth of several follicles. When a couple does not want a multiple pregnancy, the use of hCG is excluded.
The drug, which is sold in cartridges, is convenient to use, since a woman can independently carry out the procedure at home. In order to eliminate the risk of developing fatty atrophy, it is recommended to alternate the place for the injection. It is advisable to conduct the first injection in a medical institution, together with a doctor.
Performance Reviews
Before thinking about the need for hormone replacement therapy, it is important to find out which hormone stimulates ovulation and whether there are deficiencies in its production by the woman’s body in vivo. Reviews of doctors agree that independent attempts to identify and cure various deviations in the work of the reproductive system lead to a deterioration in the overall picture of the disease. Alternative methods of treatment do not always have the desired effect, and the use of drugs on the recommendation increases the time of normal ovulation.
Only an experienced specialist can tell you how to stimulate ovulation at home. , , . , .
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